SCHEMBL3133417

SCHEMBL3133417

CCN(CC)c1cc2oc3cc(=N)ccc-3nc2cc1C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 12/20 0.39
CYP1A2 P05177 1/20 0.39
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
KDM4E B2RXH2 1/20 0.34
ALDH1A1 P00352 1/20 0.34
TP53 P04637 1/20 0.34
MAPT P10636 1/20 0.34
ALOX15 P16050 1/20 0.34
CASP1 P29466 1/20 0.34
MPI P34949 1/20 0.34
BRCA1 P38398 1/20 0.34
HTT P42858 1/20 0.34
RECQL P46063 1/20 0.34
CASP7 P55210 1/20 0.34
HSD17B10 Q99714 1/20 0.34
NPC1 O15118 1/20 0.34
POLB P06746 1/20 0.34
RAB9A P51151 1/20 0.34
LATS1 O95835 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22477649 0.85 MEN1 (0.33) APPCYP1A2MEN1KMT2AKDM4E
SCHEMBL20329108 0.84 APP (0.39) APPCYP1A2MEN1KMT2AKDM4E
SCHEMBL14338730 0.82 MEN1 (0.51) APPCYP1A2MEN1KMT2AKDM4E
SCHEMBL21678115 0.82 APP (0.37) APPCYP1A2MEN1KMT2AKDM4E
SCHEMBL23701698 0.76 MEN1 (0.31) APPCYP1A2MEN1KMT2AKDM4E
SCHEMBL21678071 0.76 MEN1 (0.31) APPCYP1A2MEN1KMT2AKDM4E
SCHEMBL18216975 0.76 HSD17B10 (0.50) APPCYP1A2MEN1KMT2AKDM4E
SCHEMBL14428782 0.73 APP (0.30) APPCYP1A2
SCHEMBL21924480 0.72 APP (0.43) APPCYP1A2MEN1KMT2AKDM4E
SCHEMBL21861878 0.70 TERT (0.40) CYP1A2MEN1KMT2AKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10980729-B2 Process for dyeing keratin fibres using at least one particular azinium dye and at least one fluorescent dye L'OREAL (FR) 2021-04-20 US disclosed
US-20200246238-A1 PROCESS FOR DYEING KERATIN FIBRES USING AT LEAST ONE PARTICULAR AZINIUM DYE AND AT LEAST ONE FLUORESCENT DYE L'OREAL (FR) 2020-08-06 US disclosed
US-10619178-B2 Biosensor and production method for same ARKRAY, INC. (JP) 2020-04-14 US disclosed
EP-3290523-B1 BIOSENSOR AND PRODUCTION METHOD FOR SAME ARKRAY INC (JP) 2019-01-23 EP disclosed
WO-2018115154-A1 PROCESS FOR DYEING KERATIN FIBRES USING AT LEAST ONE PARTICULAR AZINIUM DYE AND AT LEAST ONE FLUORESCENT DYE L'OREAL (FR) 2018-06-28 WO disclosed
EP-3290523-A1 BIOSENSOR AND PRODUCTION METHOD FOR SAME ARKRAY, Inc. (JP) 2018-03-07 EP disclosed
US-20180057851-A1 Biosensor and Production Method for Same ARKRAY, INC. (JP) 2018-03-01 US disclosed
EP-1679508-B1 BIOSENSOR AND METHOD FOR PREPARATION THEREOF ARKRAY INC (JP) 2010-07-21 EP disclosed
EP-1271143-B1 Test strip having a porous filter layer ARKRAY INC (JP) 2009-05-06 EP disclosed
US-7201871-B2 Specimen having capability of separating solid component ARKRAY INC. (JP) 2007-04-10 US disclosed
US-6777243-B2 MEASURING DETECTABLE SUBSTANCE BY USING AQUEOUS REACTION SYSTEM INCLUDING FORMATION REACTION OF DETECTABLE SUBSTANCE BASED ON CHEMICAL REACTION OF ANALYTE CONTAINED IN SAMPLE; REACTING IN PRESENCE OF LAYERED INORGANIC COMPOUND ARKRAY INC. (JP) 2004-08-17 US disclosed
US-20030203503-A1 Method for measuring substance and testing piece FUKUOKA TAKAO (JP) 2003-10-30 US disclosed
US-20030180183-A1 Method for measuring substance and testing piece FUKUOKA TAKAO (JP) 2003-09-25 US disclosed
US-20030175985-A1 Method for measuring substance and testing piece FUKUOKA TAKAO (JP) 2003-09-18 US disclosed
US-20030175984-A1 Method for measuring substance and testing piece FUKUOKA TAKAO (JP) 2003-09-18 US disclosed
US-20030166295-A1 Method for measuring substance and testing piece FUKUOKA TAKAO (JP) 2003-09-04 US disclosed
US-20030044316-A1 Specimen having capability of separating solid component ARKRAY INC. (JP) 2003-03-06 US disclosed
EP-1271143-A1 SPECIMEN HAVING CAPABILITY OF SEPARATING SOLID COMPONENT ARKRAY, Inc. (JP) 2003-01-02 EP disclosed
EP-0860695-A9 METHOD OF MEASUREMENT OF MATERIAL AND TESTPIECE KABUSHIKI KAISHA KYOTO DAIICHI KAGAKU (JP) 2001-10-17 EP disclosed
EP-0860695-A1 METHOD OF MEASUREMENT OF MATERIAL AND TESTPIECE KABUSHIKI KAISHA KYOTO DAIICHI KAGAKU (JP) 1998-08-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200246238-A1 PROCESS FOR DYEING KERATIN FIBRES USING AT LEAST ONE PARTICULAR AZINIUM DYE AND AT LEAST ONE FLUORESCENT DYE KRT18, GLA, JUP APP 1144/4885CYP1A2 1093/4885MEN1 2360/4885
US-10980729-B2 Process for dyeing keratin fibres using at least one particular azinium dye and at least one fluorescent dye KRT18, GLA, JUP APP 1144/4885CYP1A2 1093/4885MEN1 2360/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.