Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 10/20 | 0.37 |
| ▸ | HPGDS | O60760 | 3/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | IL2 | P60568 | 1/20 | 0.34 |
| ▸ | ITK | Q08881 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 3/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.34 |
| ▸ | CCNC | P24863 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.34 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.34 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.34 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | IRAK3 | Q9Y616 | 1/20 | 0.34 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30258434 | 0.91 | CRBN (0.43) | CRBNHPGDSDDB1ASAH1 | |
| Hydrochloric Acid SCHEMBL30258073 | 0.90 | CRBN (0.43) | CRBNHPGDSDDB1ASAH1 | |
| SCHEMBL31333550 | 0.89 | CRBN (0.38) | CRBNHPGDSARHTR1ASLC6A2 | |
| SCHEMBL31333811 | 0.85 | CRBN (0.40) | CRBNHPGDSARDDB1ASAH1 | |
| SCHEMBL31333529 | 0.85 | CRBN (0.40) | CRBNHTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL31333737 | 0.84 | ENPP2 (0.42) | — | |
| SCHEMBL31333735 | 0.83 | CRBN (0.41) | CRBNARITKESR1DDB1 | |
| SCHEMBL31333265 | 0.83 | CRBN (0.47) | CRBNDDB1CCNCCDK8IRAK1 | |
| SCHEMBL31333950 | 0.80 | CRBN (0.40) | CRBNARESR1DDB1 | |
| SCHEMBL31334494 | 0.79 | CRBN (0.40) | CRBNARESR1DDB1ASAH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |