SCHEMBL31333737

SCHEMBL31333737

O=C1CC[C@@H](n2c(=O)oc3cc(N4CCC(CCN5CCN(C(=O)OCc6ccccc6)CC5)CC4)ccc32)C(=O)N1

nearest known ligand 0.42

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ ENPP2 Q13822 2/20 0.42
▸ TMEM97 Q5BJF2 13/20 0.40
▸ SIGMAR1 Q99720 13/20 0.40
▸ ATXN2 Q99700 1/20 0.39
▸ CHRM4 P08173 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31333265 0.84 CRBN (0.47) —
SCHEMBL31334240 0.84 CRBN (0.37) —
SCHEMBL22291366 0.83 CRBN (0.54) —
SCHEMBL29919803 0.82 SIGMAR1 (0.45) TMEM97SIGMAR1
SCHEMBL29919906 0.82 SIGMAR1 (0.45) TMEM97SIGMAR1
SCHEMBL29919831 0.81 CRBN (0.47) TMEM97SIGMAR1
SCHEMBL29919877 0.81 CRBN (0.54) TMEM97SIGMAR1
SCHEMBL31333484 0.80 CRBN (0.48) —
SCHEMBL29547197 0.80 CRBN (0.54) TMEM97SIGMAR1
SCHEMBL27098632 0.80 CRBN (0.54) TMEM97SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 — — EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 — — WO disclosed
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