Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE2 | O96020 | 2/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.33 |
| ▸ | CDK2 | P24941 | 2/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 3/20 | 0.31 |
| ▸ | FLT3 | P36888 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.31 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.30 |
| ▸ | CDK1 | P06493 | 2/20 | 0.30 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.30 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.30 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.30 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.30 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.30 |
| ▸ | CDK9 | P50750 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31489663 | 0.90 | JAK2 (0.34) | PTGDR2JAK2FLT3SMN1; SMN2KDM4E | |
| SCHEMBL31489637 | 0.83 | MKNK1 (0.39) | JAK2SMN1; SMN2KDM4EGPR55 | |
| SCHEMBL31489493 | 0.80 | CREBBP (0.32) | PTGDR2 | |
| SCHEMBL31489816 | 0.76 | CYP11B2 (0.40) | JAK2SMN1; SMN2KDM4E | |
| SCHEMBL31489553 | 0.76 | CYP11B2 (0.40) | JAK2SMN1; SMN2KDM4E | |
| SCHEMBL31489309 | 0.76 | PDK2 (0.34) | SMN1; SMN2KDM4E | |
| SCHEMBL31489570 | 0.75 | MKNK1 (0.40) | JAK2SMN1; SMN2KDM4EGPR55 | |
| SCHEMBL31334291 | 0.72 | GRM4 (0.45) | SMN1; SMN2KDM4E | |
| SCHEMBL30595813 | 0.72 | JAK2 (0.33) | CCNE2CCNE1CDK2JAK2FLT3 | |
| SCHEMBL31489550 | 0.72 | CYP26A1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072395-A1 | TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-04-03 | — | — | WO | disclosed |