Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | PREP | P48147 | 1/20 | 0.32 |
| ▸ | SPR | P35270 | 5/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.30 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
| ▸ | ASGR1 | P07306 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31701244 | 1.00 | HSD11B1 (0.41) | HSD11B1CHRM2CHRM1CHRM3JAK2 | |
| SCHEMBL12731232 | 0.92 | HSD11B1 (0.42) | HSD11B1CHRM2CHRM1CHRM3JAK2 | |
| SCHEMBL12731230 | 0.92 | HSD11B1 (0.42) | HSD11B1CHRM2CHRM1CHRM3JAK2 | |
| SCHEMBL12731684 | 0.92 | HSD11B1 (0.42) | HSD11B1CHRM2CHRM1CHRM3JAK2 | |
| SCHEMBL31702033 | 0.90 | HSD11B1 (0.44) | HSD11B1CHRM2CHRM1CHRM3JAK2 | |
| SCHEMBL4162009 | 0.87 | HSD11B1 (0.43) | HSD11B1CHRM2CHRM1CHRM3KDM4D | |
| SCHEMBL4162004 | 0.87 | HSD11B1 (0.43) | HSD11B1CHRM2CHRM1CHRM3KDM4D | |
| SCHEMBL14371565 | 0.86 | HSD11B1 (0.43) | HSD11B1CHRM2CHRM1CHRM3KDM4D | |
| SCHEMBL132146 | 0.84 | HSD11B1 (0.42) | HSD11B1CHRM2CHRM1CHRM3JAK2 | |
| SCHEMBL135183 | 0.82 | HSD11B1 (0.42) | HSD11B1CHRM2CHRM1CHRM3JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |