SCHEMBL31334412

SCHEMBL31334412

Fc1cnc(Cl)nc1C1=CCCNC1

nearest known ligand 0.42

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 12/20 0.42
HTR2C P28335 5/20 0.38
HTR2B P41595 5/20 0.38
CHRM2 P08172 1/20 0.35
CHRM3 P20309 1/20 0.35
FAAH O00519 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21605780 0.67 CHRM2 (0.43) HTR2AHTR2CHTR2BCHRM2CHRM3
SCHEMBL31357935 0.66 HTR2A (0.50) HTR2AHTR2CHTR2B
SCHEMBL25770059 0.66 HTR2A (0.67) HTR2AHTR2CHTR2BFAAH
SCHEMBL31358123 0.65 HTR2A (0.57) HTR2AHTR2CHTR2BFAAH
SCHEMBL7617737 0.65 CHRM1 (0.50) HTR2AHTR2CHTR2BCHRM2CHRM3
SCHEMBL31334343 0.65 MAPT (0.33) SMN1; SMN2KMT2A
SCHEMBL31357955 0.64 HTR2A (0.58) HTR2AHTR2CHTR2B
Hydrochloric Acid SCHEMBL9728335 0.64 HTR2A (0.41) HTR2AHTR2CHTR2BCHRM2CHRM3
SCHEMBL7922055 0.64 CHRM2 (0.47) HTR2AHTR2CHTR2BCHRM2CHRM3
Hydrochloric Acid SCHEMBL7617483 0.64 CHRM1 (0.49) HTR2AHTR2CHTR2BCHRM2CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 WO disclosed