Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 14/20 | 0.58 |
| ▸ | HTR2C | P28335 | 5/20 | 0.51 |
| ▸ | HTR2B | P41595 | 5/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25770059 | 0.89 | HTR2A (0.67) | HTR2AHTR2CHTR2BADRA2AADRA2B | |
| SCHEMBL25293535 | 0.81 | HTR2A (0.62) | HTR2AHTR2CHTR2BADRA2AADRA2B | |
| SCHEMBL25243946 | 0.79 | HTR2A (0.66) | HTR2AHTR2CHTR2BHTR6 | |
| SCHEMBL25243167 | 0.71 | HTR2A (0.63) | HTR2AHTR2CHTR2B | |
| SCHEMBL25291079 | 0.71 | HTR2A (0.61) | HTR2AHTR2CHTR2BADRA2AADRA2B | |
| SCHEMBL25245902 | 0.70 | HTR2A (0.62) | HTR2AHTR2CHTR2BADRA2AHTR6 | |
| SCHEMBL25290230 | 0.70 | HTR2A (1.00) | HTR2AHTR2CHTR2B | |
| SCHEMBL25293881 | 0.70 | HTR2A (1.00) | HTR2AHTR2CHTR2B | |
| SCHEMBL25244788 | 0.68 | HTR2A (1.00) | HTR2AHTR2CHTR2B | |
| SCHEMBL25293441 | 0.68 | HTR2A (0.70) | HTR2AHTR2CHTR2BADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024259241-A1 | 5-HT2A RECEPTOR MODULATORS AND METHODS OF USE THEREOF | Transneural Therapeutics, Inc. (US) | 2024-12-19 | — | — | WO | disclosed |