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SCHEMBL31334436

SCHEMBL31334436

Cn1c(=O)n(C2CCC(=O)NC2=O)c2ccc(C3CCN(CC4CCN(CC(=O)N[C@H]5CC[C@H](Nc6ncc(Cl)c(-c7cccc(-c8ccc(F)cc8)c7)n6)CC5)CC4)CC3)cc21

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ MAPK1 P28482 17/20 0.39
▸ GRIN2B Q13224 1/20 0.36
▸ JUN P05412 1/20 0.35
▸ CDK2 P24941 1/20 0.35
▸ MAPK8 P45983 1/20 0.35
▸ MAPK9 P45984 1/20 0.35
▸ MAPK10 P53779 1/20 0.35
▸ CRBN Q96SW2 1/20 0.35
▸ CDK12 Q9NYV4 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31334361 0.93 MAPK1 (0.41) MAPK1
SCHEMBL31333626 0.88 MAPK1 (0.44) MAPK1JUNCDK2MAPK8MAPK9
SCHEMBL31334762 0.87 MAPK1 (0.36) MAPK1GRIN2BMAPK8CRBN
SCHEMBL31333932 0.86 CRBN (0.36) MAPK1GRIN2BCRBN
SCHEMBL31334132 0.86 MAPK1 (0.37) MAPK1CRBN
SCHEMBL31334680 0.85 MAPK1 (0.41) MAPK1JUNCDK2MAPK8MAPK9
SCHEMBL31335081 0.84 MAPK1 (0.36) MAPK1CRBNCDK12
SCHEMBL31334165 0.84 MAPK1 (0.39) MAPK1
SCHEMBL31334402 0.84 MAPK1 (0.37) MAPK1CRBN
SCHEMBL31334794 0.82 MAPK1 (0.41) MAPK1JUNCDK2MAPK8MAPK9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 — — EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 — — WO disclosed