Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SLC6A5 | Q9Y345 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | SLC6A9 | P48067 | 3/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31333710 | 1.00 | MAPT (0.51) | MAPTTHRBALDH1A1LMNAKMT2A | |
| SCHEMBL31333851 | 0.92 | MAPT (0.54) | MAPTTHRBALDH1A1LMNAKMT2A | |
| SCHEMBL25169527 | 0.90 | MAPT (0.60) | MAPTTHRBALDH1A1LMNAKMT2A | |
| SCHEMBL31333796 | 0.86 | ALDH1A1 (0.55) | MAPTTHRBALDH1A1LMNAKMT2A | |
| SCHEMBL31333664 | 0.85 | DRD2 (0.51) | MAPTTHRBALDH1A1LMNAKMT2A | |
| SCHEMBL31334092 | 0.85 | ALDH1A1 (0.48) | MAPTTHRBALDH1A1LMNAKMT2A | |
| SCHEMBL26495535 | 0.84 | MAPT (0.55) | MAPTTHRBALDH1A1LMNAKMT2A | |
| SCHEMBL30425302 | 0.84 | MAPT (0.55) | MAPTTHRBALDH1A1LMNAKMT2A | |
| SCHEMBL31334229 | 0.84 | MAPT (0.46) | MAPTTHRBALDH1A1LMNAKMT2A | |
| SCHEMBL31333288 | 0.83 | MAPT (0.43) | MAPTALDH1A1LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |