Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 2/20 | 0.48 |
| ▸ | JAK3 | P52333 | 1/20 | 0.48 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 2/20 | 0.40 |
| ▸ | CCND1 | P24385 | 2/20 | 0.40 |
| ▸ | CCND3 | P30281 | 2/20 | 0.40 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.40 |
| ▸ | MAPK3 | P27361 | 6/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | ITK | Q08881 | 1/20 | 0.38 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | CDK9 | P50750 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31333355 | 0.93 | BTK (0.47) | BTKJAK3DYRK2CDK4CCND1 | |
| SCHEMBL31333214 | 0.92 | BTK (0.47) | BTKJAK3DYRK2CDK4CCND1 | |
| SCHEMBL31333561 | 0.89 | MAPK3 (0.43) | BTKDYRK2MAPK1MAPK3CCNT1 | |
| SCHEMBL31333828 | 0.89 | MAPK3 (0.43) | BTKDYRK2MAPK1MAPK3CCNT1 | |
| SCHEMBL31333240 | 0.88 | JAK3 (0.49) | BTKJAK3DYRK2CDK4CCND1 | |
| SCHEMBL31334825 | 0.86 | JAK3 (0.48) | BTKJAK3DYRK2CDK4CCND1 | |
| SCHEMBL31335048 | 0.84 | MAPK3 (0.41) | BTKDYRK2MAPK1MAPK3CCNA2 | |
| SCHEMBL31334731 | 0.84 | MAPK3 (0.41) | BTKDYRK2MAPK1MAPK3CCNA2 | |
| SCHEMBL31334123 | 0.82 | MAPK3 (0.47) | MAPK1MAPK3CCNT1CDK2CDK9 | |
| SCHEMBL31334771 | 0.81 | SYK (0.42) | DYRK2MAPK1MAPK3MAPK8CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |