Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 2/20 | 0.47 |
| ▸ | JAK3 | P52333 | 1/20 | 0.47 |
| ▸ | MAPK3 | P27361 | 5/20 | 0.44 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
| ▸ | CCND1 | P24385 | 1/20 | 0.40 |
| ▸ | CCND3 | P30281 | 1/20 | 0.40 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.39 |
| ▸ | SYK | P43405 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | ITK | Q08881 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31334463 | 0.93 | BTK (0.48) | BTKJAK3MAPK3DYRK2CDK4 | |
| SCHEMBL31333214 | 0.92 | BTK (0.47) | BTKJAK3MAPK3DYRK2CDK4 | |
| SCHEMBL31334771 | 0.89 | SYK (0.42) | MAPK3DYRK2MAPK1SYK | |
| SCHEMBL31333240 | 0.88 | JAK3 (0.49) | BTKJAK3DYRK2CDK4CCND1 | |
| SCHEMBL31334825 | 0.85 | JAK3 (0.48) | BTKJAK3MAPK3DYRK2CDK4 | |
| SCHEMBL31334502 | 0.84 | MAPK3 (0.39) | BTKMAPK3MAPK1SYK | |
| SCHEMBL31333828 | 0.81 | MAPK3 (0.43) | BTKMAPK3DYRK2MAPK1 | |
| SCHEMBL31333561 | 0.81 | MAPK3 (0.43) | BTKMAPK3DYRK2MAPK1 | |
| SCHEMBL31333422 | 0.81 | MAPK3 (0.44) | MAPK3MAPK1SYK | |
| SCHEMBL31334543 | 0.80 | SYK (0.44) | JAK3MAPK3DYRK2MAPK1SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |