Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 5/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.39 |
| ▸ | MYC | P01106 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29407780 | 0.88 | PDK4 (0.47) | USP30ESR2NR1H2MAPK1PDK4 | |
| SCHEMBL22658966 | 0.88 | PDK4 (0.47) | USP30ESR2NR1H2MAPK1PDK4 | |
| SCHEMBL22945388 | 0.87 | USP30 (0.48) | USP30ESR2NR1H2MAPK1PDK4 | |
| SCHEMBL19459096 | 0.85 | ESR2 (0.45) | USP30ESR2NR1H2MAPK1PDK4 | |
| SCHEMBL6352947 | 0.85 | MAPK1 (0.49) | USP30ESR2NR1H2MAPK1PDK4 | |
| SCHEMBL21361618 | 0.85 | MGAT2 (0.44) | USP30ESR2NR1H2MAPK1PDK4 | |
| SCHEMBL30952437 | 0.85 | MGAT2 (0.44) | USP30ESR2NR1H2MAPK1PDK4 | |
| SCHEMBL21425203 | 0.83 | MAPK1 (0.41) | USP30ESR2NR1H2MAPK1PDK4 | |
| SCHEMBL22944628 | 0.83 | NAMPT (0.48) | USP30ESR2NR1H2MAPK1PDK4 | |
| SCHEMBL4019549 | 0.82 | PTGDR2 (0.42) | USP30ESR2NR1H2MAPK1PDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |