Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAT2 | Q10469 | 1/20 | 0.44 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | ABL2 | P42684 | 1/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21361618 | 1.00 | MGAT2 (0.44) | MGAT2DGAT2MEN1KMT2AABL1 | |
| SCHEMBL21425203 | 0.89 | MAPK1 (0.41) | MGAT2DGAT2USP30ESR2MAPK1 | |
| SCHEMBL29941117 | 0.88 | PDK4 (0.47) | MGAT2DGAT2MEN1KMT2AABL1 | |
| SCHEMBL21767871 | 0.88 | PDK4 (0.47) | MGAT2DGAT2MEN1KMT2AABL1 | |
| SCHEMBL15649776 | 0.88 | ALDH1A1 (0.43) | ALDH1A1ESR2STSMAPK1NR1H2 | |
| SCHEMBL22945388 | 0.86 | USP30 (0.48) | USP30ESR2MAPK1NR1H2PDK4 | |
| SCHEMBL31334489 | 0.85 | USP30 (0.45) | DGAT2MEN1KMT2AUSP30ESR2 | |
| SCHEMBL11195135 | 0.85 | ALDH1A1 (0.48) | MEN1KMT2AALDH1A1MAPK1KDM4E | |
| SCHEMBL28516672 | 0.84 | NCOA1 (0.44) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL6352947 | 0.84 | MAPK1 (0.49) | USP30ESR2MAPK1NR1H2PDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112262129-B | Triazacyclododecanesulfonamide (\"TCD\") based protein secretion inhibitors | 科智生命科学公司 | 2024-05-14 | — | — | CN | disclosed |