Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 5/20 | 0.32 |
| ▸ | GRM1 | Q13255 | 5/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL39349 | 0.83 | PDK4 (0.43) | USP30PDK4GRM5GRM1P2RX7 | |
| Carbamic Acid SCHEMBL30167549 | 0.79 | GRM5 (0.41) | USP30PDK4GRM5GRM1P2RX7 | |
| SCHEMBL986465 | 0.79 | P2RX7 (0.44) | USP30PDK4GRM5GRM1P2RX7 | |
| SCHEMBL23538597 | 0.79 | USP30 (0.39) | USP30PDK4GRM5GRM1USP2 | |
| SCHEMBL25322440 | 0.77 | HPGD (0.38) | PDK4GRM5GRM1ALDH1A1LMNA | |
| SCHEMBL12194027 | 0.76 | GRM5 (0.45) | PDK4GRM5GRM1USP2SMN1; SMN2 | |
| SCHEMBL31510697 | 0.76 | HPGD (0.40) | PDK4GRM5GRM1ALDH1A1LMNA | |
| SCHEMBL20131001 | 0.76 | PDK4 (0.40) | USP30PDK4GRM5GRM1USP2 | |
| SCHEMBL1763807 | 0.76 | USP30 (0.41) | USP30PDK4GRM5GRM1P2RX7 | |
| SCHEMBL27241645 | 0.76 | USP30 (0.41) | USP30MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |