Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 2/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 11/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30165670 | 0.78 | MAP4K1 (0.43) | MAP4K1JAK2TYK2PTGS2CYP3A4 | |
| SCHEMBL19994364 | 0.78 | MAP4K1 (0.43) | MAP4K1JAK2TYK2PTGS2CYP3A4 | |
| SCHEMBL30165667 | 0.78 | MAP4K1 (0.43) | MAP4K1JAK2TYK2PTGS2CYP3A4 | |
| SCHEMBL25676559 | 0.78 | MAP4K1 (0.46) | MAP4K1PTGS2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL31334907 | 0.77 | PARP1 (0.44) | MAP4K1JAK2TYK2CYP3A4CYP2D6 | |
| SCHEMBL15845742 | 0.76 | GAA (0.51) | PIK3CDPIK3CA | |
| SCHEMBL31333899 | 0.75 | IDH1 (0.37) | TYK2PIK3CDPIK3CAPIK3CB | |
| SCHEMBL28894717 | 0.75 | PTGS2 (0.36) | MAP4K1JAK2TYK2PTGS2CYP2C9 | |
| SCHEMBL31334661 | 0.74 | RAF1 (0.40) | MAP4K1JAK2TYK2PTGS2CYP3A4 | |
| SCHEMBL6405329 | 0.72 | CRBN (0.49) | MAP4K1JAK2PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |