SCHEMBL31334704

SCHEMBL31334704

CC(C)(C)OC(=O)N1CCC(Nc2ncc(F)c(-c3cccc(N4CCOC4=O)c3)n2)CC1

nearest known ligand 0.48

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 6/20 0.48
DYRK2 Q92630 6/20 0.45
CDK4 P11802 2/20 0.44
CCND1 P24385 2/20 0.44
CCND3 P30281 1/20 0.44
CDK6 Q00534 1/20 0.44
IDH1 O75874 1/20 0.41
IDH2 P48735 1/20 0.41
USP30 Q70CQ3 3/20 0.41
CDK1 P06493 1/20 0.41
CDK2 P24941 1/20 0.41
ADORA2A P29274 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31333906 0.95 MAPK1 (0.47) MAPK1DYRK2CDK4CCND1CCND3
SCHEMBL31333605 0.90 MAPK1 (0.49) MAPK1DYRK2CDK4CCND1CCND3
SCHEMBL31334622 0.89 MAPK1 (0.48) MAPK1DYRK2CDK4CCND1CCND3
SCHEMBL31334451 0.89 MAPK1 (0.48) MAPK1DYRK2CDK4CCND1CCND3
SCHEMBL31334958 0.89 MAPK1 (0.45) MAPK1DYRK2CDK4CCND1CCND3
SCHEMBL31334854 0.87 MAPK1 (0.52) MAPK1DYRK2CDK4CCND1CCND3
SCHEMBL31333999 0.86 DYRK2 (0.47) MAPK1DYRK2CDK4CCND1CCND3
SCHEMBL31334037 0.85 MAPK1 (0.45) MAPK1CDK4CDK6CDK1CDK2
SCHEMBL31333654 0.85 DYRK2 (0.49) MAPK1DYRK2CDK4CCND1CCND3
SCHEMBL31334514 0.85 USP30 (0.52) MAPK1DYRK2CDK4CCND1CCND3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 WO disclosed