Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.52 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.49 |
| ▸ | DYRK2 | Q92630 | 5/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.46 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.46 |
| ▸ | CDK4 | P11802 | 1/20 | 0.45 |
| ▸ | CCND1 | P24385 | 1/20 | 0.45 |
| ▸ | CCND3 | P30281 | 1/20 | 0.45 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | VCP | P55072 | 1/20 | 0.44 |
| ▸ | IDH1 | O75874 | 1/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31333654 | 0.92 | DYRK2 (0.49) | MAPK1USP30DYRK2GPR119ALK | |
| SCHEMBL31333605 | 0.89 | MAPK1 (0.49) | MAPK1USP30DYRK2CDK4CCND1 | |
| SCHEMBL31334264 | 0.89 | MAPK1 (0.52) | MAPK1USP30DYRK2CDK4CCND1 | |
| SCHEMBL31334222 | 0.88 | JAK2 (0.51) | MAPK1ALKCDK4CCND1CCND3 | |
| SCHEMBL31334704 | 0.87 | MAPK1 (0.48) | MAPK1USP30DYRK2CDK4CCND1 | |
| SCHEMBL31334514 | 0.87 | USP30 (0.52) | MAPK1USP30DYRK2GPR119CDK4 | |
| SCHEMBL31333906 | 0.86 | MAPK1 (0.47) | MAPK1USP30DYRK2CDK4CCND1 | |
| SCHEMBL31334823 | 0.85 | DYRK2 (0.52) | MAPK1USP30DYRK2CDK4CCND1 | |
| SCHEMBL31334516 | 0.85 | MAPK1 (0.48) | MAPK1USP30DYRK2ALKCDK4 | |
| SCHEMBL31334203 | 0.83 | JAK2 (0.53) | MAPK1CDK4CCND1CCND3CDK6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |