Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | TYK2 | P29597 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | CDK2 | P24941 | 4/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.36 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.36 |
| ▸ | SYK | P43405 | 3/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
| ▸ | CCND1 | P24385 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | CDK7 | P50613 | 2/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | RAF1 | P04049 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31333886 | 0.93 | MAP4K1 (0.39) | MAP4K1JAK2JAK1TYK2JAK3 | |
| SCHEMBL31334530 | 0.93 | MAP4K1 (0.39) | MAP4K1JAK2JAK1TYK2JAK3 | |
| SCHEMBL31334176 | 0.91 | MAP4K1 (0.40) | MAP4K1JAK2JAK1TYK2JAK3 | |
| SCHEMBL31334437 | 0.88 | MAPK1 (0.43) | MAP4K1PTGS2MAPK1RAF1BRAF | |
| SCHEMBL31334057 | 0.87 | RAF1 (0.40) | JAK2JAK1TYK2JAK3MAPK3 | |
| SCHEMBL31334114 | 0.86 | MAP4K1 (0.42) | MAP4K1JAK2JAK1TYK2JAK3 | |
| SCHEMBL31334500 | 0.85 | MAP4K1 (0.41) | MAP4K1JAK2JAK1TYK2JAK3 | |
| SCHEMBL31333754 | 0.84 | CDK9 (0.42) | MAP4K1PTGS2MAPK1CDK2CDK1 | |
| SCHEMBL31334585 | 0.83 | MAP4K1 (0.42) | MAP4K1JAK2MAPK1CDK2CDK1 | |
| SCHEMBL31334841 | 0.83 | CDK2 (0.42) | MAP4K1MAPK3MAPK1CDK2CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |