Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 5/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.39 |
| ▸ | SYK | P43405 | 4/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31334100 | 0.93 | MAP4K1 (0.42) | MAP4K1PIK3CDMAPK1JAK2JAK1 | |
| SCHEMBL31333902 | 0.91 | MAP4K1 (0.43) | MAP4K1PIK3CDMAPK1JAK2JAK1 | |
| SCHEMBL31334836 | 0.91 | MAP4K1 (0.43) | MAP4K1PIK3CDMAPK1JAK2JAK1 | |
| SCHEMBL31333618 | 0.91 | MAP4K1 (0.42) | MAP4K1PIK3CDMAPK1JAK2PTGS2 | |
| SCHEMBL31333301 | 0.91 | MAP4K1 (0.42) | MAP4K1PIK3CDMAPK1JAK2PTGS2 | |
| SCHEMBL31334057 | 0.88 | RAF1 (0.40) | MAPK1JAK2JAK1TYK2JAK3 | |
| SCHEMBL31334737 | 0.88 | MAPK1 (0.39) | PIK3CDMAPK1SYKCCNA2CDK2 | |
| SCHEMBL31334776 | 0.86 | MAP4K1 (0.39) | MAP4K1MAPK1JAK2JAK1TYK2 | |
| SCHEMBL31333841 | 0.85 | MAP4K1 (0.44) | MAP4K1PIK3CDMAPK1JAK2JAK1 | |
| SCHEMBL31334543 | 0.85 | SYK (0.44) | MAPK1JAK2JAK1JAK3SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |