Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1B | P35368 | 2/20 | 0.41 |
| ▸ | ABL1 | P00519 | 2/20 | 0.36 |
| ▸ | BTK | Q06187 | 2/20 | 0.36 |
| ▸ | BCR | P11274 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | EML4 | Q9HC35 | 1/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | NPY2R | P49146 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31487841 | 0.81 | ADRA1B (0.45) | ADRA1BMAPTKMT2AMEN1LMNA | |
| SCHEMBL31487444 | 0.77 | ADRA1B (0.41) | ADRA1BMAPTKMT2AMEN1HTR1A | |
| SCHEMBL31333389 | 0.77 | CRBN (0.49) | — | |
| SCHEMBL30902688 | 0.75 | MAPKAPK2 (0.45) | ADRA1BMAPTKMT2AMEN1LMNA | |
| SCHEMBL31334987 | 0.74 | MEN1 (0.38) | ADRA1BMAPTKMT2AMEN1ADRA1D | |
| SCHEMBL31334799 | 0.74 | AXL (0.38) | ADRA1BMAPTKMT2AMEN1OPRM1 | |
| SCHEMBL31487740 | 0.73 | ADRA1B (0.38) | ADRA1BMAPTKMT2AMEN1HTR1A | |
| SCHEMBL31216624 | 0.72 | NPY2R (0.39) | ADRA1BMAPTKMT2AMEN1NPY2R | |
| SCHEMBL157877 | 0.70 | MAPT (0.56) | ABL1BTKBCRMAPTLMNA | |
| SCHEMBL27225161 | 0.69 | DDB1 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |