SCHEMBL31334799

SCHEMBL31334799

NC1CCN(C2CCN(c3ccc(NN4C(=O)CCCC4=O)cc3F)CC2)CC1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AXL P30530 2/20 0.38
KCNH2 Q12809 1/20 0.37
EGFR P00533 1/20 0.36
MEN1 O00255 1/20 0.35
MAPT P10636 1/20 0.35
KMT2A Q03164 1/20 0.35
OPRM1 P35372 3/20 0.35
OPRK1 P41145 3/20 0.35
OPRD1 P41143 2/20 0.35
OGFRL1 Q5TC84 2/20 0.35
ADRA1B P35368 1/20 0.35
OPRL1 P41146 1/20 0.34
NPY2R P49146 4/20 0.34
CDK4 P11802 2/20 0.34
CSF1R P07333 1/20 0.34
CDK6 Q00534 1/20 0.34
GAA P10253 1/20 0.33
CCR4 P51679 1/20 0.33
CCNT1 O60563 1/20 0.33
CCND1 P24385 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31487444 0.84 ADRA1B (0.41) MEN1MAPTKMT2AADRA1BGAA
SCHEMBL31334987 0.83 MEN1 (0.38) AXLKCNH2EGFRMEN1MAPT
SCHEMBL31334791 0.81 HTR7 (0.34) ADRA1BOPRL1
SCHEMBL30902688 0.77 MAPKAPK2 (0.45) MEN1MAPTKMT2AADRA1BCDK4
SCHEMBL31216624 0.77 NPY2R (0.39) MEN1MAPTKMT2AADRA1BNPY2R
SCHEMBL31334646 0.76 DDB1 (0.49)
SCHEMBL31334636 0.76 DDB1 (0.49)
SCHEMBL31334802 0.74 ADRA1B (0.41) MEN1MAPTKMT2AOPRM1OPRK1
SCHEMBL31487841 0.73 ADRA1B (0.45) MEN1MAPTKMT2AADRA1BKDM4E
SCHEMBL31335013 0.73 AXL (0.37) AXLKCNH2EGFRCDK4CSF1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 WO disclosed