SCHEMBL31334849

SCHEMBL31334849

CC(C)(C)OC(=O)NC1CCN(CC2CCN(c3ccc([N+](=O)[O-])cc3F)CC2)CC1

nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 5/20 0.54
ALDH1A1 P00352 6/20 0.45
MAPT P10636 4/20 0.45
LMNA P02545 2/20 0.45
THRB P10828 1/20 0.45
KMT2A Q03164 1/20 0.44
KCNA3 P22001 1/20 0.42
DRD3 P35462 1/20 0.41
SLC6A9 P48067 1/20 0.41
SLC6A5 Q9Y345 1/20 0.41
HTT P42858 1/20 0.41
POLB P06746 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27224905 0.93 DRD2 (0.59) DRD2ALDH1A1MAPTLMNATHRB
SCHEMBL13419542 0.92 DRD2 (0.54) DRD2ALDH1A1MAPTLMNATHRB
SCHEMBL30915181 0.92 DRD2 (0.54) DRD2ALDH1A1MAPTLMNATHRB
SCHEMBL30915152 0.88 DRD2 (0.53) DRD2ALDH1A1MAPTLMNATHRB
SCHEMBL4287750 0.88 ALDH1A1 (0.51) DRD2ALDH1A1MAPTLMNATHRB
SCHEMBL4287745 0.88 ALDH1A1 (0.51) DRD2ALDH1A1MAPTLMNATHRB
SCHEMBL5232224 0.88 ALDH1A1 (0.51) DRD2ALDH1A1MAPTLMNATHRB
SCHEMBL31333624 0.87 DRD2 (0.53) DRD2KCNA3DRD3
SCHEMBL31334575 0.86 ALDH1A1 (0.47) ALDH1A1MAPTLMNATHRBKMT2A
SCHEMBL31334687 0.86 MAPT (0.53) ALDH1A1MAPTLMNATHRBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 WO disclosed