Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK2 | Q92630 | 6/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CDK4 | P11802 | 2/20 | 0.48 |
| ▸ | CCND1 | P24385 | 2/20 | 0.48 |
| ▸ | CCND3 | P30281 | 1/20 | 0.48 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.48 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.47 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.46 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.46 |
| ▸ | IDH1 | O75874 | 1/20 | 0.46 |
| ▸ | IDH2 | P48735 | 1/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.45 |
| ▸ | SYK | P43405 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31334514 | 0.95 | USP30 (0.52) | DYRK2MAPK1CDK4CCND1CCND3 | |
| SCHEMBL31334054 | 0.91 | CCNT1 (0.52) | DYRK2MAPK1DNMT3ACCNT1USP30 | |
| SCHEMBL31335014 | 0.88 | CCNT1 (0.49) | MAPK1DNMT3ACCNT1PTPN2PTPN1 | |
| SCHEMBL31333654 | 0.86 | DYRK2 (0.49) | DYRK2MAPK1CDK4CCND1CCND3 | |
| SCHEMBL31334988 | 0.85 | ALOX5AP (0.47) | DYRK2MAPK1CDK4CCND1CCND3 | |
| SCHEMBL31334854 | 0.85 | MAPK1 (0.52) | DYRK2MAPK1CDK4CCND1CCND3 | |
| SCHEMBL31334296 | 0.85 | MAPK1 (0.46) | DYRK2MAPK1DNMT3ACCNT1USP30 | |
| SCHEMBL31334516 | 0.84 | MAPK1 (0.48) | DYRK2MAPK1CDK4CCND1CCND3 | |
| SCHEMBL31333217 | 0.84 | MAPK8 (0.54) | MAPK1CCNT1USP30CDK2 | |
| SCHEMBL31334274 | 0.83 | MAPK1 (0.46) | MAPK1CDK4CCND1CCND3CDK6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |