Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.62 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.62 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.50 |
| ▸ | PPIB | P23284 | 1/20 | 0.49 |
| ▸ | PPIA | P62937 | 1/20 | 0.49 |
| ▸ | PPID | Q08752 | 1/20 | 0.49 |
| ▸ | PPIG | Q13427 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL752665 | 0.92 | CYP4F2 (0.72) | CYP4F2CYP4A11CYP4Z1PPIBPPIA | |
| Hydrochloric Acid SCHEMBL6982675 | 0.91 | CYP4F2 (0.70) | CYP4F2CYP4A11CYP4Z1PPIBPPIA | |
| SCHEMBL10736550 | 0.86 | CYP4F2 (0.64) | CYP4F2CYP4A11CYP4Z1FFAR1LMNA | |
| SCHEMBL2773677 | 0.86 | FFAR1 (0.66) | CYP4F2CYP4A11CYP4Z1FFAR1MAPT | |
| SCHEMBL10730919 | 0.85 | CYP4F2 (0.62) | CYP4F2CYP4A11CYP4Z1FFAR1LMNA | |
| SCHEMBL3146690 | 0.84 | CYP4F2 (0.51) | CYP4F2CYP4A11CYP4Z1ALDH1A1POLB | |
| SCHEMBL4654742 | 0.84 | CYP4F2 (0.60) | CYP4F2CYP4A11CYP4Z1FFAR1LMNA | |
| SCHEMBL11527718 | 0.84 | CYP4F2 (0.60) | CYP4F2CYP4A11CYP4Z1FFAR1LMNA | |
| SCHEMBL68902 | 0.83 | CYP4F2 (0.85) | CYP4F2CYP4A11CYP4Z1LMNAMAPT | |
| SCHEMBL1467579 | 0.83 | CYP4F2 (0.58) | CYP4F2CYP4A11CYP4Z1PPIBPPIA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120238750-A1 | AROMATIC COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. | 2012-09-20 | — | — | US | disclosed |
| US-8236826-B2 | Diarylether derivatives as antitumor agents | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2012-08-07 | — | — | US | disclosed |
| US-8188277-B2 | Aromatic compounds for suppressing the generation of collagen | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2012-05-29 | — | — | US | disclosed |
| US-20100004438-A1 | DIARYLETHER DERIVATIVES AS ANTITUMOR AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2010-01-07 | — | — | US | disclosed |
| EP-1957073-A2 | MEDICINAL DRUG | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2008-08-20 | — | — | EP | disclosed |
| US-20070270422-A1 | Aromatic Compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-11-22 | — | — | US | disclosed |
| WO-2007066784-A2 | DIARYLETHER DERIVATIVES AS ANTITUMOR AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-06-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120238750-A1 | AROMATIC COMPOUND | CBR1, CBR3, CYP1A1 | CYP4F2 546/4885CYP4A11 159/4885CYP4Z1 362/4885 |
| US-20100004438-A1 | DIARYLETHER DERIVATIVES AS ANTITUMOR AGENTS | ROS1, CBR1, CBR3 | CYP4F2 2279/4885CYP4A11 1486/4885CYP4Z1 1687/4885 |
| US-20070270422-A1 | Aromatic Compounds | COL1A1, COL2A1, COL14A1 | CYP4F2 435/4885CYP4A11 183/4885CYP4Z1 509/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.