Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK6 | Q00534 | 11/20 | 0.42 |
| ▸ | CDK4 | P11802 | 9/20 | 0.42 |
| ▸ | CSF1R | P07333 | 5/20 | 0.42 |
| ▸ | CDK2 | P24941 | 3/20 | 0.42 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.42 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.42 |
| ▸ | CCNK | O75909 | 1/20 | 0.42 |
| ▸ | CDK7 | P50613 | 1/20 | 0.42 |
| ▸ | CDK9 | P50750 | 1/20 | 0.42 |
| ▸ | CCNH | P51946 | 1/20 | 0.42 |
| ▸ | CCND1 | P24385 | 3/20 | 0.41 |
| ▸ | CCND3 | P30281 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.40 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.40 |
| ▸ | IDH1 | O75874 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.39 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.39 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31334261 | 0.95 | CDK6 (0.40) | CDK6CDK4CSF1RCDK2CCNA2 | |
| SCHEMBL31334329 | 0.89 | CDK9 (0.42) | CDK6CDK4CDK2CCNA2CDK5 | |
| SCHEMBL31334455 | 0.89 | CDK9 (0.42) | CDK6CDK4CDK2CCNA2CDK5 | |
| SCHEMBL31333633 | 0.89 | MAP4K1 (0.47) | CDK6CDK2CCNA2MAPK1MAPK3 | |
| SCHEMBL31333839 | 0.87 | MAPK1 (0.42) | CDK4CDK2CCNA2CDK5CDK5R1 | |
| SCHEMBL31334958 | 0.86 | MAPK1 (0.45) | CDK6CDK4CSF1RCDK2CCNA2 | |
| SCHEMBL31334703 | 0.86 | MAPK1 (0.42) | CDK4CDK2CCNA2CDK5CDK5R1 | |
| SCHEMBL31334173 | 0.86 | MAPK1 (0.42) | CDK4CDK2CCNA2CDK5CDK5R1 | |
| SCHEMBL31333290 | 0.84 | CDK9 (0.41) | CDK6CDK4CDK2CCNA2CDK5 | |
| SCHEMBL31334120 | 0.84 | SYK (0.45) | CDK6CDK4CDK2CCNA2CDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |