Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | RXRG | P48443 | 1/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 9/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.41 |
| ▸ | PDE4A | P27815 | 4/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GCK | P35557 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3133528 | 0.97 | GRM2 (0.44) | RXRARXRBRXRGGRM2PDE4B | |
| SCHEMBL3121497 | 0.96 | RXRA (0.48) | RXRARXRBRXRGGRM2PDE4B | |
| SCHEMBL1159028 | 0.93 | GRM2 (0.44) | GRM2PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL3131461 | 0.91 | PDE4A (0.47) | RXRARXRBRXRGGRM2PDE4B | |
| SCHEMBL3133561 | 0.91 | GRM2 (0.42) | RXRARXRBRXRGGRM2PDE4B | |
| SCHEMBL3200102 | 0.89 | PDE4B (0.45) | GRM2PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL4190635 | 0.88 | GRM2 (0.44) | RXRARXRBRXRGGRM2PDE4B | |
| SCHEMBL3117619 | 0.88 | RXRA (0.41) | RXRARXRBRXRGGRM2PDE4B | |
| SCHEMBL3132076 | 0.88 | GRM2 (0.44) | RXRAGRM2PDE4BPDE4APDE4C | |
| SCHEMBL3123134 | 0.87 | ALDH1A1 (0.46) | GRM2PDE4BPDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010003084-A2 | PHOSPHODIESTERASE 4 INHIBITORS | MEMORY PHARMACEUTICALS CORPORATION (US) | 2010-01-07 | — | — | WO | disclosed |