Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.31 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31335604 | 0.83 | TDP1 (0.43) | TDP1L3MBTL1TSHR | |
| SCHEMBL31335652 | 0.75 | TDP1 (0.36) | TDP1L3MBTL1TSHR | |
| SCHEMBL27032900 | 0.73 | ALDH1A1 (0.40) | TDP1L3MBTL1TSHR | |
| SCHEMBL26604723 | 0.70 | TDP1 (0.36) | TDP1L3MBTL1TSHR | |
| SCHEMBL26604780 | 0.67 | ALDH1A1 (0.38) | TDP1L3MBTL1TSHR | |
| SCHEMBL26604867 | 0.65 | TDP1 (0.34) | TDP1L3MBTL1TSHR | |
| SCHEMBL26604963 | 0.65 | TDP1 (0.34) | TDP1L3MBTL1TSHR | |
| SCHEMBL16072319 | 0.64 | PDE4B (0.35) | TDP1TSHR | |
| SCHEMBL1640544 | 0.63 | TDP1 (0.39) | TDP1L3MBTL1TSHR | |
| SCHEMBL13083105 | 0.63 | TDP1 (0.39) | TDP1L3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4720038-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2026-04-08 | — | — | EP | disclosed |
| WO-2024246496-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2024-12-05 | — | — | WO | disclosed |