Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.38 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31335562 | 0.83 | TDP1 (0.35) | TDP1L3MBTL1TSHR | |
| SCHEMBL31335652 | 0.79 | TDP1 (0.36) | TDP1L3MBTL1ALDH1A1MAPTCYP3A4 | |
| SCHEMBL23655043 | 0.70 | ALDH1A1 (0.48) | TDP1L3MBTL1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL26604723 | 0.69 | TDP1 (0.36) | TDP1L3MBTL1ALDH1A1MAPTHPGD | |
| SCHEMBL31014100 | 0.67 | ALDH1A1 (0.41) | TDP1L3MBTL1ALDH1A1HSD17B10MAPT | |
| SCHEMBL26604721 | 0.67 | ALDH1A1 (0.41) | TDP1L3MBTL1ALDH1A1HSD17B10MAPT | |
| SCHEMBL1640544 | 0.67 | TDP1 (0.39) | TDP1L3MBTL1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL13083105 | 0.67 | TDP1 (0.39) | TDP1L3MBTL1ALDH1A1HSD17B10MAPT | |
| SCHEMBL18231233 | 0.67 | KMT2A (0.42) | TDP1L3MBTL1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL15348611 | 0.67 | TDP1 (0.58) | TDP1L3MBTL1KMT2AALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4720038-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2026-04-08 | — | — | EP | disclosed |
| WO-2024246496-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2024-12-05 | — | — | WO | disclosed |