Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.50 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.50 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.44 |
| ▸ | GLRB | P48167 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | RARB | P10826 | 2/20 | 0.40 |
| ▸ | RARG | P13631 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17378811 | 1.00 | ALOX15 (0.50) | ALOX15ALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL31336086 | 0.85 | GLRA3 (0.44) | ALOX15ALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL31335768 | 0.85 | GLRA3 (0.44) | ALOX15ALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL17896567 | 0.85 | GLRA3 (0.42) | ALOX15ALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL31335744 | 0.82 | ALDH1A1 (0.56) | ALOX15ALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL21694101 | 0.82 | ALOX15 (0.62) | ALOX15ALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL5002782 | 0.82 | ALDH1A1 (0.56) | ALOX15ALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL15459959 | 0.81 | GLRA3 (0.42) | ALOX15ALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL31335968 | 0.81 | MAPT (0.46) | ALOX15ALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL17378789 | 0.81 | MAPT (0.46) | ALOX15ALDH1A1KDM4EMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4720038-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2026-04-08 | — | — | EP | disclosed |
| WO-2024246496-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2024-12-05 | — | — | WO | disclosed |