Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 2/20 | 0.36 |
| ▸ | BACE1 | P56817 | 4/20 | 0.33 |
| ▸ | ROR1 | Q01973 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.32 |
| ▸ | ACLY | P53396 | 1/20 | 0.31 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24132612 | 0.90 | ALDH1A1 (0.38) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL30401888 | 0.88 | ERN1 (0.41) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL23043278 | 0.83 | PRKDC (0.38) | ERN1BACE1LMNAALDH1A1ACLY | |
| SCHEMBL22633207 | 0.81 | PRKDC (0.42) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL655644 | 0.81 | ERN1 (0.58) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL2025457 | 0.79 | ERN1 (0.38) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL14054810 | 0.79 | KMT2A (0.36) | LMNAALDH1A1 | |
| SCHEMBL28418398 | 0.77 | ERN1 (0.57) | ERN1BACE1LMNAALDH1A1CYP1A2 | |
| SCHEMBL8231856 | 0.76 | L3MBTL1 (0.44) | ALDH1A1 | |
| SCHEMBL5605156 | 0.76 | ALDH1A1 (0.36) | LMNAALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4720038-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2026-04-08 | — | — | EP | disclosed |
| WO-2024246496-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2024-12-05 | — | — | WO | disclosed |