Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | HPGDS | O60760 | 1/20 | 0.35 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26121608 | 1.00 | JAK2 (0.39) | JAK2SMN1; SMN2GAAALDH1A1KDM4E | |
| SCHEMBL26126071 | 0.78 | ALDH1A1 (0.36) | JAK2SMN1; SMN2GAAALDH1A1KDM4E | |
| SCHEMBL31336073 | 0.78 | ALDH1A1 (0.36) | JAK2SMN1; SMN2GAAALDH1A1KDM4E | |
| SCHEMBL27296579 | 0.74 | CYP19A1 (0.41) | ALDH1A1KDM4EL3MBTL1GRM5EGFR | |
| SCHEMBL31473424 | 0.74 | CYP19A1 (0.41) | ALDH1A1KDM4EL3MBTL1GRM5EGFR | |
| SCHEMBL2737290 | 0.72 | ALDH1A1 (0.46) | GAAALDH1A1KDM4EHPGDL3MBTL1 | |
| SCHEMBL6160870 | 0.71 | MEN1 (0.58) | SMN1; SMN2ALDH1A1KDM4EHPGDL3MBTL1 | |
| SCHEMBL22481508 | 0.71 | KDM4E (0.36) | ALDH1A1KDM4EHPGDL3MBTL1HTT | |
| SCHEMBL31399246 | 0.70 | GRM5 (0.47) | ALDH1A1KDM4EHPGDL3MBTL1HTT | |
| SCHEMBL26123199 | 0.70 | GRM5 (0.47) | ALDH1A1KDM4EHPGDL3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250230166-A1 | OXADIAZOLE HDAC6 INHIBITORS AND USES THEREOF | EIKONIZO THERAPEUTICS, INC. (US) | 2025-07-17 | — | — | US | disclosed |
| CN-119451678-A | Inhibition of histone deacetylase 6 (HDAC 6) | 艾科尼佐治疗股份有限公司 | 2025-02-14 | — | — | CN | disclosed |
| CN-119212707-A | Oxadiazole HDAC6 inhibitors and uses thereof | 艾科尼佐治疗股份有限公司 | 2024-12-27 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250230166-A1 | OXADIAZOLE HDAC6 INHIBITORS AND USES THEREOF | HDAC6, HDAC1, HDAC11 | JAK2 2543/4885SMN1; SMN2 498/4885GAA 121/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.