Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | APLNR | P35414 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 2/20 | 0.32 |
| ▸ | KMO | O15229 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | LDHA | P00338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14966974 | 0.84 | POLB (0.49) | ALDH1A1POLBKDM4EHTTGAA | |
| SCHEMBL31336040 | 0.78 | JAK2 (0.39) | ALDH1A1GRM5KDM4EHTTGAA | |
| SCHEMBL14967105 | 0.76 | CHRNB2 (0.41) | POLBHTTLMNATDP1 | |
| SCHEMBL14102858 | 0.74 | GBA1 (0.36) | ALDH1A1KDM4EGAASMN1; SMN2MEN1 | |
| SCHEMBL31541656 | 0.74 | GBA1 (0.36) | ALDH1A1KDM4EGAASMN1; SMN2MEN1 | |
| SCHEMBL20525062 | 0.73 | GBA1 (0.33) | ALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL15006213 | 0.73 | GBA1 (0.35) | ALDH1A1KDM4EMEN1KMT2ANPC1 | |
| SCHEMBL18674122 | 0.71 | GBA1 (0.34) | ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL31473349 | 0.70 | S1PR3 (0.35) | ALDH1A1KDM4ENPC1RAB9ARXFP1 | |
| SCHEMBL17364436 | 0.70 | GBA1 (0.41) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119451678-A | Inhibition of histone deacetylase 6 (HDAC 6) | 艾科尼佐治疗股份有限公司 | 2025-02-14 | — | — | CN | disclosed |
| CN-119212707-A | Oxadiazole HDAC6 inhibitors and uses thereof | 艾科尼佐治疗股份有限公司 | 2024-12-27 | — | — | CN | disclosed |