Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SMARCA2 | P51531 | 2/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ACP1 | P24666 | 1/20 | 0.43 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | BCL3 | P20749 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21744257 | 0.89 | PIK3CD (0.43) | TSHRKMT2AMEN1LMNASMARCA2 | |
| SCHEMBL24913864 | 0.75 | CYP2A13 (0.53) | KMT2AMEN1LMNAHPGDKDM4E | |
| SCHEMBL30101416 | 0.74 | HRH3 (0.53) | TSHRPOLBKDM4E | |
| Hydrochloric Acid SCHEMBL30368364 | 0.73 | CYP2A13 (0.51) | KMT2AMEN1LMNAHPGDKDM4E | |
| Hydrochloric Acid SCHEMBL29008593 | 0.73 | CYP2A13 (0.51) | KMT2AMEN1LMNAHPGDKDM4E | |
| SCHEMBL2342146 | 0.73 | ABHD6 (0.51) | TSHRKMT2AMEN1LMNAHPGD | |
| SCHEMBL383947 | 0.73 | HRH3 (0.61) | TSHRKDM4EHTTUSP2SIGMAR1 | |
| SCHEMBL11604511 | 0.72 | KDM4E (0.67) | TSHRKMT2AMEN1LMNASMARCA2 | |
| SCHEMBL13500541 | 0.72 | KDM4E (0.55) | TSHRKMT2AMEN1LMNASMARCA2 | |
| SCHEMBL6528435 | 0.72 | KMT2A (0.51) | TSHRKMT2AMEN1LMNASMARCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4720038-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2026-04-08 | — | — | EP | disclosed |
| WO-2024246496-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2024-12-05 | — | — | WO | disclosed |