Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | RBP4 | P02753 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31335662 | 1.00 | PTGDR2 (0.37) | PTGDR2EGFRCLCN2NR1I2CYP2C8 | |
| SCHEMBL5008843 | 0.87 | PTGDR2 (0.42) | PTGDR2EGFRCLCN2TSHRHSD17B10 | |
| SCHEMBL31335940 | 0.79 | KDM4E (0.32) | PTGDR2EGFRKDM4EALDH1A1MAPT | |
| SCHEMBL15459960 | 0.77 | ALDH1A1 (0.47) | NR1I2CYP2C8IDO1HSD17B10LCK | |
| SCHEMBL4522132 | 0.75 | CLCN2 (0.47) | EGFRCLCN2TSHRHSD17B10KDM4E | |
| SCHEMBL31335851 | 0.75 | ALDH1A1 (0.35) | EGFRTSHRKDM4EALDH1A1MAPT | |
| SCHEMBL17896567 | 0.74 | GLRA3 (0.42) | KDM4EALDH1A1MAPTPOLBFABP4 | |
| SCHEMBL22245067 | 0.74 | HSD17B10 (0.46) | EGFRCLCN2TSHRHSD17B10LCK | |
| SCHEMBL3156615 | 0.74 | EGFR (0.55) | EGFRHSD17B10KDM4EALDH1A1NR1H4 | |
| SCHEMBL6331248 | 0.72 | CYP3A4 (0.47) | PTGDR2TSHRKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4720038-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2026-04-08 | — | — | EP | disclosed |
| WO-2024246496-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2024-12-05 | — | — | WO | disclosed |