Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24925873 | 0.81 | HTR2A (0.36) | KDM4EALDH1A1HTR2AMAPT | |
| SCHEMBL31336065 | 0.79 | PTGDR2 (0.37) | KDM4EALDH1A1EGFRPTGDR2MAPT | |
| SCHEMBL31335662 | 0.79 | PTGDR2 (0.37) | KDM4EALDH1A1EGFRPTGDR2MAPT | |
| SCHEMBL26932098 | 0.78 | HTR2A (0.42) | KDM4EALDH1A1HTR2AMAPT | |
| SCHEMBL31167218 | 0.78 | ALDH1A1 (0.34) | KDM4EALDH1A1EGFRHTR2AMAPT | |
| SCHEMBL31335851 | 0.77 | ALDH1A1 (0.35) | KDM4EALDH1A1EGFRMAPT | |
| SCHEMBL5324019 | 0.77 | PTGDR2 (0.57) | ALDH1A1PTGDR2 | |
| SCHEMBL8715503 | 0.77 | HTR2C (0.36) | KDM4EALDH1A1EGFRHTR2AMAPT | |
| SCHEMBL15980355 | 0.76 | HTR2A (0.39) | KDM4EALDH1A1EGFRHTR2AMAPT | |
| SCHEMBL321526 | 0.74 | AAK1 (0.40) | KDM4EALDH1A1HTR2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4720038-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2026-04-08 | — | — | EP | disclosed |
| WO-2024246496-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2024-12-05 | — | — | WO | disclosed |