Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 10/20 | 0.43 |
| ▸ | BCAT1 | P54687 | 2/20 | 0.41 |
| ▸ | ACLY | P53396 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24314219 | 0.85 | BCAT1 (0.42) | KAT6ABCAT1MEN1KMT2ANPC1 | |
| SCHEMBL31723071 | 0.85 | BCAT1 (0.42) | KAT6ABCAT1MEN1KMT2ANPC1 | |
| SCHEMBL31336172 | 0.83 | BCAT1 (0.47) | KAT6ABCAT1MEN1KMT2ANPC1 | |
| SCHEMBL26073873 | 0.82 | KAT6A (0.42) | KAT6ABCAT1MEN1KMT2ANPC1 | |
| SCHEMBL26073862 | 0.80 | KAT6A (0.35) | KAT6AACLYMEN1KMT2ANPC1 | |
| SCHEMBL22601111 | 0.80 | KMT2A (0.42) | KAT6ABCAT1MEN1KMT2ANPC1 | |
| SCHEMBL26074523 | 0.78 | TSHR (0.42) | KAT6AMEN1KMT2ADRD3 | |
| SCHEMBL31336129 | 0.76 | TSHR (0.49) | KAT6AMEN1KMT2ANPC1RAB9A | |
| SCHEMBL26073875 | 0.76 | TSHR (0.41) | MEN1KMT2ARAB9A | |
| SCHEMBL26074510 | 0.76 | TSHR (0.42) | KAT6AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250051343-A1 | INHIBITORS OF THE MYST FAMILY OF LYSINE ACETYL TRANSFERASES | Isosterix, Inc. | 2025-02-13 | — | — | US | disclosed |
| CN-119301096-A | Inhibitors of MYST family lysine acetyltransferase | 伊索斯泰里克斯公司 | 2025-01-10 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250051343-A1 | INHIBITORS OF THE MYST FAMILY OF LYSINE ACETYL TRANSFERASES | KAT6A, KAT6B, KAT2A | KAT6A 1/4885BCAT1 134/4885ACLY 2678/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.