Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT1 | P54687 | 3/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | FBP1 | P09467 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31723071 | 1.00 | BCAT1 (0.42) | BCAT1PTGER4CCR2FBP1PTGES | |
| SCHEMBL31336123 | 0.85 | KAT6A (0.43) | BCAT1CCR2KAT6AMEN1KMT2A | |
| SCHEMBL22588427 | 0.85 | BCAT1 (0.43) | BCAT1PTGER4FBP1MMP2HPGD | |
| SCHEMBL30538408 | 0.84 | BCAT1 (0.55) | BCAT1MMP2HPGDKDM4EMEN1 | |
| SCHEMBL31723074 | 0.84 | KDM4E (0.51) | BCAT1PTGER4FBP1HPGDKDM4E | |
| SCHEMBL24313791 | 0.84 | KDM4E (0.51) | BCAT1PTGER4FBP1HPGDKDM4E | |
| SCHEMBL24313562 | 0.84 | NPC1 (0.46) | BCAT1PTGER4FBP1MMP2HPGD | |
| SCHEMBL22588433 | 0.84 | BCAT1 (0.48) | BCAT1PTGER4FBP1MMP2HPGD | |
| SCHEMBL22587808 | 0.82 | PTGER4 (0.46) | BCAT1PTGER4MMP2HPGDKDM4E | |
| SCHEMBL24313971 | 0.81 | ALDH1A1 (0.41) | BCAT1PTGER4FBP1MMP2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081842-A1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | THE BROAD INSTITUTE, INC. (US) | 2022-04-21 | — | — | WO | disclosed |