Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | GLP1R | P43220 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1059732 | 1.00 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1MAPK1POLBOPRK1 | |
| SCHEMBL1710186 | 0.90 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1MAPK1POLBOPRK1 | |
| SCHEMBL24737978 | 0.89 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1MAPK1POLBOPRK1 | |
| SCHEMBL10736055 | 0.88 | SMN1; SMN2 (0.61) | SMN1; SMN2ALDH1A1MAPK1POLBKMT2A | |
| SCHEMBL8840383 | 0.87 | POLB (0.57) | SMN1; SMN2ALDH1A1MAPK1POLBOPRK1 | |
| SCHEMBL10004036 | 0.85 | CYP3A4 (0.45) | SMN1; SMN2ALDH1A1MAPK1CYP3A4TDP1 | |
| SCHEMBL31353159 | 0.84 | POLB (0.50) | SMN1; SMN2ALDH1A1MAPK1POLBKMT2A | |
| SCHEMBL14625956 | 0.84 | POLB (0.50) | SMN1; SMN2ALDH1A1MAPK1POLBKMT2A | |
| SCHEMBL2630833 | 0.83 | ALDH1A1 (0.53) | SMN1; SMN2ALDH1A1MAPK1POLBKMT2A | |
| SCHEMBL14661145 | 0.83 | POLB (0.47) | SMN1; SMN2ALDH1A1MAPK1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120020134-A | Heterocyclic carbonyl derivative regulator, preparation method and application thereof | 江苏豪森药业集团有限公司 | 2025-05-20 | — | — | CN | disclosed |
| CN-119546580-A | Heteroaryl compounds for the treatment of pain | 沃泰克斯药物股份有限公司 | 2025-02-28 | — | — | CN | disclosed |