Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14625956 | 1.00 | POLB (0.50) | POLBSMN1; SMN2ALDH1A1MAPK1KDM4E | |
| SCHEMBL10736055 | 0.85 | SMN1; SMN2 (0.61) | POLBSMN1; SMN2ALDH1A1MAPK1KDM4E | |
| SCHEMBL3191583 | 0.84 | SMN1; SMN2 (0.61) | POLBSMN1; SMN2ALDH1A1MAPK1KDM4E | |
| SCHEMBL1059732 | 0.84 | SMN1; SMN2 (0.50) | POLBSMN1; SMN2ALDH1A1MAPK1KDM4E | |
| SCHEMBL13363312 | 0.84 | POLB (0.53) | POLBSMN1; SMN2ALDH1A1MAPK1KDM4E | |
| SCHEMBL31336305 | 0.84 | SMN1; SMN2 (0.50) | POLBSMN1; SMN2ALDH1A1MAPK1KDM4E | |
| SCHEMBL14661145 | 0.80 | POLB (0.47) | POLBSMN1; SMN2ALDH1A1MAPK1KDM4E | |
| SCHEMBL1628027 | 0.80 | ALDH1A1 (0.47) | POLBSMN1; SMN2ALDH1A1MAPK1GAA | |
| SCHEMBL8697727 | 0.80 | ALDH1A1 (0.53) | SMN1; SMN2ALDH1A1MAPK1KDM4EGAA | |
| SCHEMBL1169230 | 0.79 | SMN1; SMN2 (0.47) | POLBSMN1; SMN2ALDH1A1MAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-121586713-A | Quinoline derivatives and pharmaceutical compositions thereof for the treatment of diseases | 百济神州(苏州)生物科技有限公司 | 2026-02-27 | — | — | CN | disclosed |
| WO-2025021217-A1 | QUINOLINE DERIVATIVES AND PHARMARCEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF DISEASE | BEIGENE SWITZERLAND GMBH (CH) | 2025-01-30 | — | — | WO | disclosed |