Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 12/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.38 |
| ▸ | PRNP | P04156 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.33 |
| ▸ | GRM5 | P41594 | 2/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31336839 | 0.82 | CYP11B2 (0.36) | CYP11B2CYP11B1PRNPDYRK1A | |
| SCHEMBL31336944 | 0.76 | CYP11B2 (0.38) | CYP11B2CYP11B1BRD4 | |
| SCHEMBL19207031 | 0.75 | HCRTR1 (0.42) | POLBGRM5 | |
| SCHEMBL253745 | 0.74 | MAPT (0.49) | POLB | |
| SCHEMBL31336683 | 0.73 | GRM5 (0.43) | POLBGRM5 | |
| SCHEMBL31336769 | 0.71 | JMJD6 (0.39) | POLBGRM5 | |
| SCHEMBL31336707 | 0.71 | GPBAR1 (0.38) | CYP11B2POLBGRM5 | |
| SCHEMBL23147354 | 0.70 | GRM5 (0.41) | POLBGRM5 | |
| SCHEMBL31336692 | 0.69 | KDM4E (0.39) | HCAR2POLB | |
| SCHEMBL4772395 | 0.68 | HCAR2 (0.42) | HCAR2CYP11B2CYP11B1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4688154-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | BIAL - Portela & Ca., S.A. (PT) | 2026-02-11 | — | — | EP | claimed |
| WO-2025023851-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | BIAL - PORTELA & CA., S.A. (PT) | 2025-01-30 | — | — | WO | claimed |
| EP-4688154-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | BIAL - Portela & Ca., S.A. (PT) | 2026-02-11 | — | — | EP | disclosed |
| WO-2025023851-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | BIAL - PORTELA & CA., S.A. (PT) | 2025-01-30 | — | — | WO | disclosed |