SCHEMBL31336705

SCHEMBL31336705

O=C1c2ccccc2OCC1C(F)(F)F

nearest known ligand 0.54

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 15/20 0.54
MAOB P27338 2/20 0.50
PKM P14618 1/20 0.43
TSHR P16473 1/20 0.43
SIGMAR1 Q99720 2/20 0.42
HTR1A P08908 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8607856 0.79 CYP19A1 (0.50) CYP19A1MAOBPKMTSHRSIGMAR1
SCHEMBL8470409 0.74 CYP19A1 (0.49) CYP19A1MAOBPKMTSHRSIGMAR1
SCHEMBL7148065 0.74 LTB4R (0.44) CYP19A1MAOB
SCHEMBL18415628 0.74 CYP19A1 (0.61) CYP19A1MAOBPKMTSHRSIGMAR1
SCHEMBL13701613 0.74 CYP19A1 (0.56) CYP19A1MAOBPKMTSHRSIGMAR1
SCHEMBL28948127 0.73 CYP19A1 (0.47) CYP19A1MAOBPKMTSHR
SCHEMBL768947 0.73 CYP19A1 (0.59) CYP19A1MAOBPKMTSHRSIGMAR1
SCHEMBL2381366 0.73 CYP19A1 (0.59) CYP19A1MAOBPKMTSHRSIGMAR1
SCHEMBL15147097 0.73 CYP19A1 (0.59) CYP19A1MAOBPKMTSHRSIGMAR1
SCHEMBL7241604 0.73 CYP19A1 (0.59) CYP19A1MAOBPKMTSHRSIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119350284-A Photocatalytic synthesis method of benzodihydropyran-4-ketone compound containing trifluoromethyl 湖南科技学院 2025-01-24 CN disclosed