Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.36 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30775080 | 0.83 | L3MBTL1 (0.49) | L3MBTL1ALOX15HTTNPSR1 | |
| SCHEMBL607604 | 0.83 | L3MBTL1 (0.49) | L3MBTL1ALOX15HTTNPSR1 | |
| SCHEMBL31336774 | 0.82 | L3MBTL1 (0.44) | L3MBTL1ALOX15HTTKDM4EALDH1A1 | |
| SCHEMBL15229409 | 0.79 | L3MBTL1 (0.42) | L3MBTL1ALOX15HTTNPSR1 | |
| SCHEMBL31336873 | 0.79 | L3MBTL1 (0.42) | L3MBTL1ALOX15HTTKDM4EALDH1A1 | |
| SCHEMBL267964 | 0.74 | NPSR1 (0.48) | L3MBTL1KDM4EALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL8320350 | 0.74 | NPSR1 (0.48) | L3MBTL1ALOX15HTTKDM4EALDH1A1 | |
| SCHEMBL29756221 | 0.74 | NPSR1 (0.48) | L3MBTL1KDM4EALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL15955973 | 0.73 | RPS6KB1 (0.47) | KDM4EALDH1A1HSD17B10SMN1; SMN2HPGD | |
| SCHEMBL31336812 | 0.73 | ALOX15 (0.42) | L3MBTL1ALOX15HTTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4688154-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | BIAL - Portela & Ca., S.A. (PT) | 2026-02-11 | — | — | EP | disclosed |
| EP-4688155-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | Bial-Portela & CA, S.A. (PT) | 2026-02-11 | — | — | EP | disclosed |
| WO-2025023852-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | BIAL - PORTELA & CA., S.A. (PT) | 2025-01-30 | — | — | WO | disclosed |
| WO-2025023851-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | BIAL - PORTELA & CA., S.A. (PT) | 2025-01-30 | — | — | WO | disclosed |