Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31336718 | 0.85 | ALDH1A1 (0.41) | ALOX15ALDH1A1L3MBTL1KMT2ANPSR1 | |
| SCHEMBL2491494 | 0.72 | S1PR4 (0.48) | S1PR4HTTALDH1A1KMT2ATP53 | |
| SCHEMBL31372703 | 0.72 | L3MBTL1 (0.42) | S1PR4ALOX15HTTALDH1A1L3MBTL1 | |
| SCHEMBL30775080 | 0.72 | L3MBTL1 (0.49) | S1PR4ALOX15HTTL3MBTL1NPSR1 | |
| SCHEMBL607604 | 0.72 | L3MBTL1 (0.49) | S1PR4ALOX15HTTL3MBTL1NPSR1 | |
| SCHEMBL1424613 | 0.71 | NQO2 (0.46) | S1PR4ALDH1A1L3MBTL1KMT2ANPSR1 | |
| SCHEMBL31336711 | 0.69 | ALDH1A1 (0.43) | ALOX15ALDH1A1L3MBTL1KMT2ATP53 | |
| SCHEMBL16114981 | 0.69 | POLB (0.46) | HTTALDH1A1L3MBTL1KMT2ANPSR1 | |
| SCHEMBL21702310 | 0.68 | NPSR1 (0.43) | S1PR4ALDH1A1L3MBTL1KMT2ANPSR1 | |
| SCHEMBL610102 | 0.68 | S1PR4 (0.56) | S1PR4ALDH1A1L3MBTL1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026106499-A1 | OREXIN RECEPTOR ANTAGONISTS: 2-AZABICYCLIC COMPOUNDS | BIAL - PORTELA & CA., S.A. (PT) | 2026-05-21 | — | — | WO | disclosed |
| EP-4688154-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | BIAL - Portela & Ca., S.A. (PT) | 2026-02-11 | — | — | EP | disclosed |
| EP-4688155-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | Bial-Portela & CA, S.A. (PT) | 2026-02-11 | — | — | EP | disclosed |
| WO-2025023852-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | BIAL - PORTELA & CA., S.A. (PT) | 2025-01-30 | — | — | WO | disclosed |
| WO-2025023851-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | BIAL - PORTELA & CA., S.A. (PT) | 2025-01-30 | — | — | WO | disclosed |