Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4158664 | 0.89 | MAPT (0.45) | MAPTALDH1A1SMN1; SMN2MAPK1HSD17B10 | |
| SCHEMBL31336842 | 0.80 | MEN1 (0.39) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL31336698 | 0.78 | RAB9A (0.39) | MAPTALDH1A1SMN1; SMN2TP53NPC1 | |
| SCHEMBL19615264 | 0.76 | ALDH1A1 (0.40) | MAPTALDH1A1SMN1; SMN2MAPK1HSD17B10 | |
| SCHEMBL24552650 | 0.75 | ALDH1A1 (0.41) | MAPTALDH1A1SMN1; SMN2MAPK1HSD17B10 | |
| SCHEMBL19615850 | 0.75 | ALDH1A1 (0.39) | MAPTALDH1A1SMN1; SMN2MAPK1HSD17B10 | |
| SCHEMBL19618984 | 0.75 | POLB (0.40) | MAPTALDH1A1SMN1; SMN2MAPK1HSD17B10 | |
| SCHEMBL19615438 | 0.74 | SLC5A1 (0.42) | MAPTALDH1A1SMN1; SMN2MAPK1HSD17B10 | |
| SCHEMBL24553235 | 0.73 | KDM4E (0.47) | MAPTALDH1A1SMN1; SMN2MAPK1HSD17B10 | |
| SCHEMBL19615387 | 0.73 | SMN1; SMN2 (0.40) | MAPTALDH1A1SMN1; SMN2MAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4688154-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | BIAL - Portela & Ca., S.A. (PT) | 2026-02-11 | — | — | EP | disclosed |
| EP-4688155-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | Bial-Portela & CA, S.A. (PT) | 2026-02-11 | — | — | EP | disclosed |
| WO-2025023851-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | BIAL - PORTELA & CA., S.A. (PT) | 2025-01-30 | — | — | WO | disclosed |
| WO-2025023852-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | BIAL - PORTELA & CA., S.A. (PT) | 2025-01-30 | — | — | WO | disclosed |