Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 2/20 | 0.49 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.49 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 10/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.48 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.43 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.40 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.40 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4207773 | 0.90 | SOS1 (0.46) | GNAI3GNAO1GNAI1GRIN2BKDM4E | |
| SCHEMBL22255203 | 0.85 | KDM4E (0.44) | GNAI3GNAO1GNAI1GRIN2BKDM4E | |
| SCHEMBL8821500 | 0.84 | GRIN2B (0.52) | GNAI3GNAO1GNAI1GRIN2BSIGMAR1 | |
| SCHEMBL17484496 | 0.84 | GRIN2B (0.48) | GNAI3GNAO1GNAI1GRIN2BSIGMAR1 | |
| SCHEMBL17484552 | 0.84 | GRIN2B (0.52) | GNAI3GNAO1GNAI1GRIN2BSIGMAR1 | |
| SCHEMBL9684908 | 0.84 | GRIN2B (0.67) | GRIN2BSIGMAR1GRIN1SOS1SLC6A2 | |
| SCHEMBL31336953 | 0.82 | GRIN2B (0.47) | GNAI3GNAO1GNAI1GRIN2BSIGMAR1 | |
| SCHEMBL30034899 | 0.81 | GRIN2B (0.48) | GNAI3GNAO1GNAI1GRIN2BSIGMAR1 | |
| SCHEMBL17277494 | 0.79 | ALDH1A1 (0.53) | GNAI3GNAO1GNAI1KDM4ESOS1 | |
| SCHEMBL2466540 | 0.78 | GRIN2B (0.51) | GRIN2BKDM4EOPRM1OPRL1SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115151550-B | External nucleotide pyrophosphatase/phosphodiesterase 1 (ENPP 1) modulators and uses thereof | 桑福德·伯纳姆·普雷比医学发现研究所 | 2024-11-22 | — | — | CN | disclosed |