Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 16/20 | 0.67 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.67 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.67 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.55 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7317273 | 0.90 | GRIN2B (0.65) | GRIN2BSIGMAR1GRIN1SOS1OPRM1 | |
| SCHEMBL31336892 | 0.84 | GNAI3 (0.49) | GRIN2BSIGMAR1GRIN1SOS1OPRM1 | |
| SCHEMBL8821500 | 0.84 | GRIN2B (0.52) | GRIN2BSIGMAR1GRIN1SOS1OPRM1 | |
| SCHEMBL17484552 | 0.84 | GRIN2B (0.52) | GRIN2BSIGMAR1GRIN1SOS1 | |
| SCHEMBL30034899 | 0.84 | GRIN2B (0.48) | GRIN2BSIGMAR1GRIN1SOS1OPRM1 | |
| SCHEMBL17484496 | 0.84 | GRIN2B (0.48) | GRIN2BSIGMAR1GRIN1SOS1SLC6A2 | |
| SCHEMBL27929338 | 0.83 | GRIN2B (0.71) | GRIN2BSIGMAR1GRIN1OPRM1OPRL1 | |
| SCHEMBL25006478 | 0.82 | GRIN2B (0.78) | GRIN2BSIGMAR1GRIN1OPRM1OPRL1 | |
| SCHEMBL31336953 | 0.82 | GRIN2B (0.47) | GRIN2BSIGMAR1GRIN1SOS1OPRM1 | |
| SCHEMBL31336897 | 0.82 | KDM4E (0.50) | GRIN2BSIGMAR1GRIN1SOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115151550-B | External nucleotide pyrophosphatase/phosphodiesterase 1 (ENPP 1) modulators and uses thereof | 桑福德·伯纳姆·普雷比医学发现研究所 | 2024-11-22 | — | — | CN | disclosed |
| US-5132311-A | Prolonging cardiac action potential repolarization | G. D. SEARLE & CO. (US) | 1992-07-21 | — | — | US | disclosed |