Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.72 |
| ▸ | MEN1 | O00255 | 10/20 | 0.72 |
| ▸ | RECQL | P46063 | 5/20 | 0.72 |
| ▸ | LMNA | P02545 | 4/20 | 0.72 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.72 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.64 |
| ▸ | PKM | P14618 | 4/20 | 0.64 |
| ▸ | POLB | P06746 | 4/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.64 |
| ▸ | RAB9A | P51151 | 2/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.64 |
| ▸ | STAT3 | P40763 | 1/20 | 0.61 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3133698 | 1.00 | MAPT (0.72) | MAPTALDH1A1KMT2AMEN1RECQL | |
| SCHEMBL3133695 | 1.00 | MAPT (0.72) | MAPTALDH1A1KMT2AMEN1RECQL | |
| SCHEMBL8189877 | 0.86 | KMT2A (0.67) | MAPTALDH1A1KMT2AMEN1RECQL | |
| SCHEMBL8189870 | 0.86 | KMT2A (0.67) | MAPTALDH1A1KMT2AMEN1RECQL | |
| SCHEMBL8189873 | 0.86 | KMT2A (0.67) | MAPTALDH1A1KMT2AMEN1RECQL | |
| SCHEMBL8190456 | 0.82 | MAPT (0.66) | MAPTALDH1A1KMT2AMEN1RECQL | |
| SCHEMBL8190455 | 0.82 | MAPT (0.66) | MAPTALDH1A1KMT2AMEN1RECQL | |
| SCHEMBL8191326 | 0.82 | MAPT (0.66) | MAPTALDH1A1KMT2AMEN1RECQL | |
| SCHEMBL3131533 | 0.81 | STAT3 (0.78) | MAPTALDH1A1KMT2AMEN1RECQL | |
| SCHEMBL3131544 | 0.81 | STAT3 (0.78) | MAPTALDH1A1KMT2AMEN1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120219613-A1 | Novel Antiviral Agents for Enveloped Viruses | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-08-30 | — | — | US | disclosed |
| WO-2010044924-A1 | NOVEL ANTIVIRAL AGENTS FOR ENVELOPED VIRUSES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-04-22 | — | — | WO | disclosed |
| WO-2000032598-A1 | METHODS AND COMPOSITIONS FOR TREATING INFLAMMATORY DISEASES UTILIZING INHIBITORS OF TUMOR NECROSIS FACTOR ACTIVITY | STRUCTURAL BIOINFORMATICS INC. (US) | 2000-06-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120219613-A1 | Novel Antiviral Agents for Enveloped Viruses | MAVS, LAMP1, HAVCR2 | MAPT 3126/4885ALDH1A1 1264/4885KMT2A 2561/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.