Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9129321 | 0.86 | ABL1 (0.47) | ABL1RIN1HSP90AB1ALDH1A1KDM4E | |
| SCHEMBL5954084 | 0.84 | HPGD (0.42) | HSP90AB1ALDH1A1KDM4EHPGDGLA | |
| SCHEMBL9911235 | 0.84 | HSP90AB1 (0.44) | HSP90AB1ALDH1A1KDM4EHPGDGLA | |
| SCHEMBL1643944 | 0.83 | EGFR (0.55) | HSP90AB1ALDH1A1KDM4EHPGDGLA | |
| SCHEMBL12650135 | 0.82 | NPC1 (0.45) | HSP90AB1ALDH1A1KDM4EHPGDGLA | |
| SCHEMBL29958566 | 0.81 | MAPT (0.43) | ABL1HSP90AB1ALDH1A1KDM4EMAPT | |
| SCHEMBL898733 | 0.81 | HPGD (0.52) | ALDH1A1KDM4EHPGDMAPTHSD17B10 | |
| SCHEMBL4635493 | 0.81 | MAPT (0.43) | ABL1HSP90AB1ALDH1A1KDM4EMAPT | |
| SCHEMBL19925456 | 0.81 | SMN1; SMN2 (0.42) | FFAR4HSP90AB1ALDH1A1KDM4EHPGD | |
| SCHEMBL29853520 | 0.81 | HPGD (0.52) | ALDH1A1KDM4EHPGDMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025050636-A1 | MACROCYCLIC PYRAZOLOPYRIMIDINE COMPOUND AND USE THEREOF | 浙江养生堂天然药物研究所有限公司 | 2025-03-13 | — | — | WO | disclosed |
| CN-119552171-A | Macrocyclic pyrazolopyrimidine compound and application thereof | 浙江养生堂天然药物研究所有限公司 | 2025-03-04 | — | — | CN | disclosed |