Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30583454 | 0.93 | NR1H2 (0.63) | NR1H2ESR2HDAC6ADORA1MEN1 | |
| SCHEMBL1648607 | 0.93 | NR1H2 (0.63) | NR1H2ESR2HDAC6ADORA1MEN1 | |
| SCHEMBL30583396 | 0.89 | ESR2 (0.65) | NR1H2ESR2HDAC6ADORA1MEN1 | |
| SCHEMBL31337577 | 0.89 | ESR2 (0.65) | NR1H2ESR2HDAC6ADORA1MEN1 | |
| SCHEMBL1650181 | 0.88 | ESR2 (0.50) | NR1H2ESR2HDAC6ADORA1MEN1 | |
| SCHEMBL1649493 | 0.86 | NR1H2 (0.62) | NR1H2ESR2HDAC6RIPK1MEN1 | |
| SCHEMBL17991072 | 0.83 | ESR2 (0.44) | NR1H2ESR2RIPK1ADORA1MEN1 | |
| SCHEMBL1263486 | 0.83 | ESR2 (0.59) | NR1H2ESR2HDAC6RIPK1MEN1 | |
| SCHEMBL18362773 | 0.83 | NR1H2 (0.58) | NR1H2ESR2HDAC6MEN1KMT2A | |
| SCHEMBL29589913 | 0.80 | NR1H2 (0.67) | NR1H2ESR2HDAC6NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110172416-A1 | AMIDINE DERIVATIVE | AJINOMOTO CO., INC. (JP) | 2011-07-14 | — | — | US | disclosed |
| EP-2311810-A1 | AMIDINE DERIVATIVE | Ajinomoto Co., Inc. (JP) | 2011-04-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172416-A1 | AMIDINE DERIVATIVE | SERPINC1, F12, F11 | NR1H2 2374/4885ESR2 4507/4885HDAC6 431/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.