Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.63 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | IGF1R | P08069 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30583454 | 1.00 | NR1H2 (0.63) | NR1H2ESR2MEN1KMT2AADORA1 | |
| SCHEMBL30583396 | 0.95 | ESR2 (0.65) | NR1H2ESR2MEN1KMT2AADORA1 | |
| SCHEMBL31337577 | 0.95 | ESR2 (0.65) | NR1H2ESR2MEN1KMT2AADORA1 | |
| SCHEMBL1648620 | 0.93 | NR1H2 (0.55) | NR1H2ESR2MEN1KMT2AADORA1 | |
| SCHEMBL1650181 | 0.90 | ESR2 (0.50) | NR1H2ESR2MEN1KMT2AADORA1 | |
| SCHEMBL18362773 | 0.89 | NR1H2 (0.58) | NR1H2ESR2MEN1KMT2AHDAC6 | |
| SCHEMBL2277894 | 0.87 | NR1H2 (0.67) | NR1H2ESR2HDAC6HDAC8MAPK1 | |
| SCHEMBL29589913 | 0.87 | NR1H2 (0.67) | NR1H2ESR2HDAC6HDAC8MAPK1 | |
| SCHEMBL31162867 | 0.86 | NR1H2 (0.57) | NR1H2ESR2MAP3K5SRD5A1SRD5A2 | |
| SCHEMBL29373737 | 0.84 | NR1H2 (0.70) | NR1H2ESR2ADORA1HDAC6HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110172416-A1 | AMIDINE DERIVATIVE | AJINOMOTO CO., INC. (JP) | 2011-07-14 | — | — | US | disclosed |
| EP-2311810-A1 | AMIDINE DERIVATIVE | Ajinomoto Co., Inc. (JP) | 2011-04-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172416-A1 | AMIDINE DERIVATIVE | SERPINC1, F12, F11 | NR1H2 2374/4885ESR2 4507/4885MEN1 349/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.